反应详情

温度

100 °C

2-Oxopropanal benzylhydrazone (2.314 mmol, 408 mg) synthesized in the same manner as in Reference Synthetic Examples 1 and 2 and (4-tert-butylphenyl)(oxo)acetaldehyde (1.929 mmol, 366.9 mg) synthesized in Reference Synthetic Example 4 were dissolved in acetic acid (9 mL) and stirred at 100° C. for about 6 hours. Then, the solvent was evaporated, and the residue was dried by means of a vacuum pump and purified by silica gel column chromatography (n-hexane/AcOEt=3/1, and 4/1) to give the desired product as a yellow solid (74.1 mg, yield 11%).

1. customsynthesized in Reference Synthetic Example 4
2. customThen, the solvent was evaporated
3. customthe residue was dried by means of a vacuum pump
4. custompurified by silica gel column chromatography (n-hexane/AcOEt=3/1, and 4/1)