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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2103892Generated: October 26, 2026

2-(3,4-Dichlorophenyl)-3-hydroxy-4-(methylcarbonyl)thiophene → Methyl 2-nitro-4-[(2-{1-[5-(3,4-dichlorophenyl)-4-hydroxy-3-thienyl]ethylidene}hydrazino)carbonyl]benzoate

https://huagongshe.com/reaction/2103892

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3,4-Dichlorophenyl)-3-hydroxy-4-(methylcarbonyl)thiopheneHCID 44207288—
Reactant4-Methoxycarbonyl-3-nitrobenzhydrazideHCID 66986356—
ProductMethyl 2-nitro-4-[(2-{1-[5-(3,4-dichlorophenyl)-4-hydroxy-3-thienyl]ethylidene}hydrazino)carbonyl]benzoateHCID 72360084—

Reaction Steps

Using 2-(3,4-dichlorophenyl)-3-hydroxy-4-methylcarbonylthiophene (100 mg, 0.35 mmol) and methyl 2-nitro-4-hydrazinocarbonylbenzoate (93 mg, 0.39 mmol) as the starting materials, the desired product was obtained in the same manner as in Synthetic Example 65 as a yellow solid (147 mg, yield 83%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576115B2
Source datasetuspto-grants-2009_08
ORD IDord-eb13051fcb9e4f1bb6cac107eb129c01
Source noteuspto-grants-2009_08