HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3,4-Dichlorophenyl)-3-hydroxy-4-(methylcarbonyl)thiophene → Methyl 2-nitro-4-[(2-{1-[5-(3,4-dichlorophenyl)-4-hydroxy-3-thienyl]ethylidene}hydrazino)carbonyl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3,4-Dichlorophenyl)-3-hydroxy-4-(methylcarbonyl)thiophene | HCID 44207288 | — |
| Reactant | 4-Methoxycarbonyl-3-nitrobenzhydrazide | HCID 66986356 | — |
| Product | Methyl 2-nitro-4-[(2-{1-[5-(3,4-dichlorophenyl)-4-hydroxy-3-thienyl]ethylidene}hydrazino)carbonyl]benzoate | HCID 72360084 | — |
Reaction Steps
Using 2-(3,4-dichlorophenyl)-3-hydroxy-4-methylcarbonylthiophene (100 mg, 0.35 mmol) and methyl 2-nitro-4-hydrazinocarbonylbenzoate (93 mg, 0.39 mmol) as the starting materials, the desired product was obtained in the same manner as in Synthetic Example 65 as a yellow solid (147 mg, yield 83%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576115B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-eb13051fcb9e4f1bb6cac107eb129c01 |
| Source note | uspto-grants-2009_08 |