HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-t-Butylphenyl)-3-hydroxy-4-methylcarbonylthiophene → Methyl 2-bromo-4-[(2-{1-[5-(4-t-butylphenyl)-4-hydroxy-3-thienyl]ethylidene}hydrazino)carbonyl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-t-Butylphenyl)-3-hydroxy-4-methylcarbonylthiophene | HCID 44207289 | — |
| Reactant | Methyl 2-bromo-4-hydrazinocarbonylbenzoate | HCID 67050217 | — |
| Product | Methyl 2-bromo-4-[(2-{1-[5-(4-t-butylphenyl)-4-hydroxy-3-thienyl]ethylidene}hydrazino)carbonyl]benzoate | HCID 72360105 | — |
Reaction Steps
Using 2-(4-t-butylphenyl)-3-hydroxy-4-methylcarbonylthiophene (55 mg, 0.20 mmol) and methyl 2-bromo-4-hydrazinocarbonylbenzoate (60 mg, 0.22 mmol) as the starting materials, the desired product was obtained in the same manner as in Synthetic Example 65 as a yellow solid (92 mg, yield 87%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576115B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-87f69ecded914ce78203c10d1dcc9b6b |
| Source note | uspto-grants-2009_08 |