HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3,4-Dichlorophenyl)-3-hydroxy-4-(methylcarbonyl)thiophene → 4-{[(2-{1-[5-(3,4-Dichlorophenyl)-4-hydroxy-3-thienyl]ethylidene}hydrazino)-carbonothioyl]amino}-2-chlorobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3,4-Dichlorophenyl)-3-hydroxy-4-(methylcarbonyl)thiophene | HCID 44207288 | — |
| Reactant | 4-Hydrazinocabonothioylamino-2-chlorobenzoic acid | HCID 86014498 | — |
| Product | 4-{[(2-{1-[5-(3,4-Dichlorophenyl)-4-hydroxy-3-thienyl]ethylidene}hydrazino)-carbonothioyl]amino}-2-chlorobenzoic acid | HCID 72360075 | — |
Reaction Steps
From 2-(3,4-dichlorophenyl)-3-hydroxy-4-methylcarbonylthiophene (50 mg, 0.17 mmol) and 4-hydrazinocabonothioylamino-2-chlorobenzoic acid (42.8 mg, 0.17 mmol), the desired product was obtained in the same manner as in Synthetic Example 50 as a pale yellow solid (61.1 mg, yield 68%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576115B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-48cd3e30d36d45b0a3c07163da53caad |
| Source note | uspto-grants-2009_08 |