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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2103916Generated: October 31, 2026

2-(3,4-Dichlorophenyl)-3-hydroxy-4-(methylcarbonyl)thiophene → 4-{[(2-{1-[5-(3,4-Dichlorophenyl)-4-hydroxy-3-thienyl]ethylidene}hydrazino)-carbonothioyl]amino}-2-chlorobenzoic acid

https://huagongshe.com/reaction/2103916

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3,4-Dichlorophenyl)-3-hydroxy-4-(methylcarbonyl)thiopheneHCID 44207288—
Reactant4-Hydrazinocabonothioylamino-2-chlorobenzoic acidHCID 86014498—
Product4-{[(2-{1-[5-(3,4-Dichlorophenyl)-4-hydroxy-3-thienyl]ethylidene}hydrazino)-carbonothioyl]amino}-2-chlorobenzoic acidHCID 72360075—

Reaction Steps

From 2-(3,4-dichlorophenyl)-3-hydroxy-4-methylcarbonylthiophene (50 mg, 0.17 mmol) and 4-hydrazinocabonothioylamino-2-chlorobenzoic acid (42.8 mg, 0.17 mmol), the desired product was obtained in the same manner as in Synthetic Example 50 as a pale yellow solid (61.1 mg, yield 68%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576115B2
Source datasetuspto-grants-2009_08
ORD IDord-48cd3e30d36d45b0a3c07163da53caad
Source noteuspto-grants-2009_08