HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → 1-(Azidomethyl)-4-methoxybenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | 4-Methyloxybenzyl chloride | HCID 69993 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1-(Azidomethyl)-4-methoxybenzene | HCID 10931767 | 75% |
Reaction Steps
64 mmol 1-(chloromethyl)-4-methoxybenzene and 90 mmol sodium azide were dissolved in 20 ml ethanol and 5 ml water, and stirred overnight at room temperature. CH2Cl2 and water were added. The organic layer was separated, dried and evaporated to give 48 mmol 1-(azidomethyl)-4-methoxybenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576165B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-902e8079dd9049f0a2205eb6f6b22ef2 |
| Source note | uspto-grants-2009_08 |