Benzoylacetone → HCID 11661329, compound

HRID 2104141Notes

Reaction equation

[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][C:3]=1[C:9]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=O.[C:17]1([C:23](=[O:28])[CH2:24][C:25](=O)[CH3:26])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[Br:8][C:5]1[CH:4]=[C:3]2[C:2](=[CH:7][CH:6]=1)[N:1]=[C:25]([CH3:26])[C:24]([C:23]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)=[O:28])=[C:9]2[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

Reactant 2

HCID 7166Benzoylacetone

HCID 996772-Amino-5-bromobenzophenone

Product 1

HCID 11661329HCID 11661329, compoundYield 61%

Procedure

The title compound was prepared from (2-Amino-5-bromo-phenyl)-phenyl-methanone [example A16] and 1-phenyl-1,3-butanedione, except that the residue was purified by spontaneous crystallization from the reaction mixture. Yield: 61%; MS: m/z=402 (M+H).

Workup

customwas purified by spontaneous crystallization from the reaction mixture

Sources & evidence

ORD record: ord-dc1e696b539d4607873de921c3941afb
Source dataset: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07576217B2

Reaction notes

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