HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-((tert-Butoxycarbonyl)amino)-3-methylbutanoic acid → (2E)-4-(1-{[(tert-butoxy)carbonyl]amino}cyclobutyl)but-2-enoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-((tert-Butoxycarbonyl)amino)-3-methylbutanoic acid | HCID 10376046 | — |
| Reactant | (1-Aminocyclobut-1-yl)acetic acid, N-BOC protected | HCID 10751878 | — |
| Product | (2E)-4-(1-{[(tert-butoxy)carbonyl]amino}cyclobutyl)but-2-enoic acid | HCID 10729698 | — |
Reaction Steps
(2E)-4-(1-(tert-Butoxycarbonylamino)cyclobutyl)but-2-enoic acid was synthesized starting with (1-(tert-butoxycarbonylamino)cyclobutyl)acetic acid analogously to the synthesis of (2E)-5-(tert-butoxycarbonylamino)-5-methylhex-2-enoic acid starting with of 3-tert-butoxycarbonylamino-3-methylbutanoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576062B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-b6592315388847fea1776e336512b77f |
| Source note | uspto-grants-2009_08 |