4-Fluoroaniline → Methyl (4-fluoroanilino)(oxo)acetate

HRID 2104379Notes

Reaction equation

[F:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1.Cl[C:10](=[O:15])[C:11]([O:13][CH3:14])=[O:12]>>[CH3:14][O:13][C:11](=[O:12])[C:10]([NH:6][C:5]1[CH:7]=[CH:8][C:2]([F:1])=[CH:3][CH:4]=1)=[O:15]

Participants

Reactant 2

HCID 97314-Fluoroaniline

HCID 79846Methyl chloroglyoxylate

Product 1

HCID 22934757Methyl (4-fluoroanilino)(oxo)acetate

Procedure

In a manner similar to that employed in Referential Example 242, the title compound was prepared from 4-fluoroaniline and methyl chlorooxoacetate.

Sources & evidence

ORD record: ord-64ccfdb4ae4849c0b9fb6886a1a5b721
Source dataset: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07576135B2

Reaction notes

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