HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroglyoxylate → 2-[(5-Chloropyridin-2-yl)(methyl)amino]-2-oxoacetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroglyoxylate | HCID 79846 | — |
| Reactant | 5-chloro-N-methylpyridin-2-amine | HCID 3837024 | — |
| Product | 2-[(5-Chloropyridin-2-yl)(methyl)amino]-2-oxoacetic acid methyl ester | HCID 59676802 | — |
Reaction Steps
The method described in Referential Example 242 was performed by use of 5-chloro-N-methyl-2-pyridinamine and methyl chlorooxoacetate, whereby the title compound was obtained. 1H-NMR(CDCl3)δ: 3.43(3H, s), 3.81(3H, s), 7.08(1H, br.s), 7.68-7.78(1H, m), 8.27(1H, br.s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576135B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-1bde30b75ffc4bbaabe01eed0da773ec |
| Source note | uspto-grants-2009_08 |