4-Chloro-3-nitroaniline → HCID 22934842, compound

HRID 2104416Notes

Reaction equation

[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].Cl[C:13](=[O:18])[C:14]([O:16]C)=[O:15]>>[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH:6][C:13](=[O:18])[C:14]([OH:16])=[O:15])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10]

Participants

Reactant 2

HCID 124774-Chloro-3-nitroaniline

HCID 79846Methyl chloroglyoxylate

Product 1

HCID 22934842HCID 22934842, compound

Procedure

In a manner similar to that described in Referential Example 242, 4-chloro-3-nitroaniline was condensed with methyl chlorooxoacetate. In a manner similar to that described in Referential Example 359, the condensed compound was hydrolyzed, whereby the title compound was obtained.

Sources & evidence

ORD record: ord-3e18ac77320e4336a50fdc6dec325f0f
Source dataset: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07576135B2

Reaction notes

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