Citric Acid → HCID 86609029, compound

Participants

Reaction Conditions

Reaction Steps

The compound obtained in Example 389 (6.26 g) was suspended in 20% hydrous ethanol (100 mL), and 1M aqueous citric acid (11.4 mL) was added to the suspension. Under stirring at 60° C., 20% hydrous ethanol was gradually added thereto to dissolve the suspension. After filtration with heating, the solution was allowed to cool to room temperature under stirring and then was left to stand for 1 day. The precipitated crystals were collected through filtration and then dried for 2 hours at room temperature under reduced pressure, and the residue was left to stand for 1 day, to thereby yield the title compound (6.95 g).

Provenance & Evidence