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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104479Generated: October 25, 2026

3-(Trifluoromethyl)phenylboronic acid → Pyridin-2-yl{8-(Trifluoromethyl)-4-[3-(Trifluoromethyl)Phenyl]Quinolin-3-yl}Methanone

https://huagongshe.com/reaction/2104479

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)phenylboronic acidHCID 2734388—
Reactant(4-Chloro-8-trifluoromethyl-quinolin-3-yl)-pyridin-2-yl-methanoneHCID 66913162—
ProductPyridin-2-yl{8-(Trifluoromethyl)-4-[3-(Trifluoromethyl)Phenyl]Quinolin-3-yl}MethanoneHCID 11408200—

Reaction Steps

This compound was prepared using the procedure of Example 1, step 5 using (4-chloro-8-trifluoromethyl-quinolin-3-yl)-pyridin-2-yl-methanone in place of [4-chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone and 3-trifluoromethylphenylboronic acid in place of phenyl boronic acid. MS (ESI) m/z 447 ([M+H]+); Anal. Calcd for C23H12F6N2O: C, 61.89; H, 2.71; N, 6.28. Found: C, 61.70; H, 2.66; N, 6.14.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-22f17cbfab044b1bab0d2763b6e86ad5
Source noteuspto-grants-2009_08