HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorophenylboronic acid → [4-(4-Chlorophenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Pyridin-2-yl)Methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorophenylboronic acid | HCID 74299 | — |
| Reactant | (4-Chloro-8-trifluoromethyl-quinolin-3-yl)-pyridin-2-yl-methanone | HCID 66913162 | — |
| Product | [4-(4-Chlorophenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Pyridin-2-yl)Methanone | HCID 11200776 | — |
Reaction Steps
This compound was prepared using the procedure of Example 1, step 5 using (4-chloro-8-trifluoromethyl-quinolin-3-yl)-pyridin-2-yl-methanone in place of [4-chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone and 4-chlorophenylboronic acid in place of phenyl boronic acid; MS (ESI) m/z 413/415 ([M+H]+); Anal. Calcd for C22H12ClF3N2O: C, 64.01; H, 2.93; N, 6.79. Found: C, 63.66; H, 3.03; N, 6.60.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576215B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-1099040f4d0c41728bed29ac630df64f |
| Source note | uspto-grants-2009_08 |