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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104526Generated: October 31, 2026

Benzaldehyde → Benzeneacetic acid,4-[[3-[3-(phenylmethyl)-8-(trifluoromethyl)-4-quinolinyl]phenoxy]methyl]-

https://huagongshe.com/reaction/2104526

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
ReactantEthyl AcetateHCID 8857—
Reactant3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenolHCID 53630755—
ProductBenzeneacetic acid,4-[[3-[3-(phenylmethyl)-8-(trifluoromethyl)-4-quinolinyl]phenoxy]methyl]-HCID 11627859—

Reaction Steps

Prepared using the procedure in Example 56 except using 3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenol instead of 4-(3-hydroxyphenyl)-8-(trifluoromethyl) quinolin-3-yl](phenyl)methanone and 4-bromomethyl-phenyl)-acetic acid ethyl ester as the halide. MS (ESI) m/z 528.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-cd30976e6c0343d1ae60363545b72daf
Source noteuspto-grants-2009_08