Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104527Generated: October 30, 2026

Benzaldehyde → [3-({3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenoxy}Methyl)Phenyl]Acetic Acid

https://huagongshe.com/reaction/2104527

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
ReactantEthyl AcetateHCID 8857—
Reactant3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenolHCID 53630755—
Product[3-({3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenoxy}Methyl)Phenyl]Acetic AcidHCID 66913959—

Reaction Steps

Prepared using the procedure in Example 56 except using 3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenol instead of 4-(3-hydroxyphenyl)-8-(trifluoromethyl) quinolin-3-yl](phenyl)methanone and 3-bromomethyl-phenyl)-acetic acid ethyl ester as the halide. MS (ES) m/z 526.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-7262b596053b4479b4370cabbd0cf9b4
Source noteuspto-grants-2009_08