methyl 3-formyl-1H-indole-6-carboxylate → HCID 66913798, compound

HRID 2104537Notes

Reaction equation

HRID 2104537 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[C:13]([C:18]([F:21])([F:20])[F:19])[CH:14]=[CH:15][CH:16]=3)[N:11]=[CH:10][C:9]=2[C:22]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[O:23])[CH:5]=[CH:6][CH:7]=1.C[O:31][C:32]([C:34]1[CH:42]=[C:41]2[C:37]([C:38]([CH:43]=O)=[CH:39][NH:40]2)=[CH:36][CH:35]=1)=[O:33]>>[C:22]([C:9]1[CH:10]=[N:11][C:12]2[C:17]([C:8]=1[C:4]1[CH:3]=[C:2]([NH:1][CH2:43][C:38]3[C:37]4[C:41](=[CH:42][C:34]([C:32]([OH:33])=[O:31])=[CH:35][CH:36]=4)[NH:40][CH:39]=3)[CH:7]=[CH:6][CH:5]=1)=[CH:16][CH:15]=[CH:14][C:13]=2[C:18]([F:21])([F:19])[F:20])(=[O:23])[C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1

Participants

3

Reactant 2

HCID 735867methyl 3-formyl-1H-indole-6-carboxylateHCID 11326798[4-(3-Aminophenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)Methanone

Product 1

HCID 66913798HCID 66913798, compound

Procedure

The title compound was prepared from [4-(3-aminophenyl)-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone and 3-formyl-1H-indole-6-carboxylic acid methyl ester according to the procedure of Example 66. MS (ESI) m/z 564.

Sources & evidence

ORD record
ord-e390447d764b44c3b19f948943c82b31
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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