Formaldehyde → HCID 16090332, compound

HRID 2104545Notes

Reaction equation

C[O:2][C:3](=[O:40])[CH2:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][NH:12][C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([C:19]3[C:28]4[C:23](=[C:24]([C:29]([F:32])([F:31])[F:30])[CH:25]=[CH:26][CH:27]=4)[N:22]=[CH:21][C:20]=3[CH2:33][C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=3)[CH:14]=2)=[CH:7][CH:6]=1.[CH2:41]=O>>[CH2:33]([C:20]1[CH:21]=[N:22][C:23]2[C:28]([C:19]=1[C:15]1[CH:14]=[C:13]([N:12]([CH2:11][C:8]3[CH:7]=[CH:6][C:5]([CH2:4][C:3]([OH:2])=[O:40])=[CH:10][CH:9]=3)[CH3:41])[CH:18]=[CH:17][CH:16]=1)=[CH:27][CH:26]=[CH:25][C:24]=2[C:29]([F:30])([F:32])[F:31])[C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1

Participants

Reactant 2

HCID 712Formaldehyde

HCID 68812736HCID 68812736, compound

Product 1

HCID 16090332HCID 16090332, compound

Procedure

The title compound was prepared from (4-{[3-(3-benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamino]-methyl}-phenyl)-acetic acid methyl ester and formaldehyde according to the procedure of Example 66. MS (ES) m/z 541.3.

Sources & evidence

ORD record: ord-fbee3986b62541889abd4f55caaaf6c6
Source dataset: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07576215B2

Reaction notes

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