4-(Aminomethyl)piperidine → HCID 66914585, compound

HRID 2104551Notes

Reaction equation

HRID 2104551 reaction equation
[C:1]([C:9]1[CH:10]=[N:11][C:12]2[C:17]([C:18]=1[C:19]1[CH:20]=[C:21]([CH:24]=[CH:25][CH:26]=1)[CH:22]=O)=[CH:16][CH:15]=[CH:14][C:13]=2[C:27]([F:30])([F:29])[F:28])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH:31]1[CH2:36][CH2:35][CH:34]([CH2:37][NH2:38])[CH2:33][CH2:32]1>>[C:2]1([C:1]([C:9]2[CH:10]=[N:11][C:12]3[C:17]([C:18]=2[C:19]2[CH:26]=[CH:25][CH:24]=[C:21]([CH2:22][NH:38][CH2:37][CH:34]4[CH2:35][CH2:36][NH:31][CH2:32][CH2:33]4)[CH:20]=2)=[CH:16][CH:15]=[CH:14][C:13]=3[C:27]([F:30])([F:28])[F:29])=[O:8])[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 235274-(Aminomethyl)piperidineHCID 860556033-[3-Benzoyl-8-(trifluoromethyl)quinolin-4-yl]benzaldehyde

Product 1

HCID 66914585HCID 66914585, compound

Procedure

The title compound was prepared from 3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]benzaldehyde and C-piperidin-4-yl-methylamine according to the procedure of Example 66. MS (ESI) m/z 504.

Sources & evidence

ORD record
ord-35af8895bda944c88d29a3071dc8152d
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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