[4-(3-Aminophenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)Methanone → HCID 90922212, compound

HRID 2104553Notes

Reaction equation

HRID 2104553 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[C:13]([C:18]([F:21])([F:20])[F:19])[CH:14]=[CH:15][CH:16]=3)[N:11]=[CH:10][C:9]=2[C:22]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[O:23])[CH:5]=[CH:6][CH:7]=1.[CH2:30]([O:32][C:33](=[O:44])[CH:34]([C:36]1[CH:41]=[CH:40][C:39]([CH:42]=O)=[CH:38][CH:37]=1)[OH:35])[CH3:31]>>[CH2:30]([O:32][C:33](=[O:44])[CH:34]([C:36]1[CH:37]=[CH:38][C:39]([CH2:42][NH:1][C:2]2[CH:7]=[CH:6][CH:5]=[C:4]([C:8]3[C:17]4[C:12](=[C:13]([C:18]([F:21])([F:19])[F:20])[CH:14]=[CH:15][CH:16]=4)[N:11]=[CH:10][C:9]=3[C:22](=[O:23])[C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=3)[CH:3]=2)=[CH:40][CH:41]=1)[OH:35])[CH3:31]

Participants

3

Reactant 2

HCID 11326798[4-(3-Aminophenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)MethanoneHCID 86598751HCID 86598751, compound

Product 1

HCID 90922212HCID 90922212, compound

Procedure

The title compound was prepared from [4-(3-amino-phenyl)-8-trifluoromethyl-quinolin-3-yl]-phenyl-methanone and (4-formyl-phenyl)-hydroxy-acetic acid ethyl ester according to the procedure of step 1, Example 66. MS (ES) m/z 585.3.

Sources & evidence

ORD record
ord-b4223cd7a0db46d0833baf435bfdd480
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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