HuagongsheHuagongshe Chemistry Print Report · For research reference only
[4-(3-Aminophenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)Methanone → 2-{4-[({3-[3-Benzoyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}Amino)Methyl]Phenyl}-2-Methylpropanoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [4-(3-Aminophenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)Methanone | HCID 11326798 | — |
| Reactant | Methyl 2-(4-formylphenyl)-2-methylpropanoate | HCID 25111210 | — |
| Product | 2-{4-[({3-[3-Benzoyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}Amino)Methyl]Phenyl}-2-Methylpropanoic Acid | HCID 23648482 | — |
Reaction Steps
The title compound was prepared from [4-(3-amino-phenyl)-8-trifluoromethyl-quinolin-3-yl]-phenyl-methanone and 2-(4-formyl-phenyl)-2-methyl-propionic acid methyl ester according to the procedure of Example 66. MS m/z 569; MS m/z 567.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576215B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-57ae2e385ad44dde8b286e8b0331a1e4 |
| Source note | uspto-grants-2009_08 |