HuagongsheHuagongshe Chemistry Print Report · For research reference only
{3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}Methanol → 3-[4-({3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Benzyl}Oxy)Phenyl]PROP-2-Ynoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | {3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}Methanol | HCID 11223110 | — |
| Reactant | (4-Hydroxymethyl-phenyl)-propynoic acid methyl ester | HCID 66913683 | — |
| Product | 3-[4-({3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Benzyl}Oxy)Phenyl]PROP-2-Ynoic Acid | HCID 66913643 | — |
Reaction Steps
The title compound was prepared from [3-(3-benzyl-8-trifluoromethyl-quinolin-4-yl)-phenyl]-methanol and (4-hydroxymethyl-phenyl)-propynoic acid methyl ester according to the procedure of Example 69. MS (ESI) m/z 538.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576215B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-e7e60275d9084440a95ed3c28711842c |
| Source note | uspto-grants-2009_08 |