HCID 4523563, compound → HCID 74078178, compound
Reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[C:13]([C:18]([F:21])([F:20])[F:19])[CH:14]=[CH:15][CH:16]=3)[N:11]=[CH:10][C:9]=2[C:22]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[O:23])[CH:5]=[CH:6][CH:7]=1.[O:30]=[C:31]1[C:35](=[CH:36][C:37]2[CH:44]=[CH:43][C:40]([CH:41]=O)=[CH:39][CH:38]=2)[S:34][C:33](=[S:45])[NH:32]1>>[C:22]([C:9]1[CH:10]=[N:11][C:12]2[C:17]([C:8]=1[C:4]1[CH:3]=[C:2]([NH:1][CH2:41][C:40]3[CH:39]=[CH:38][C:37]([CH:36]=[C:35]4[S:34][C:33](=[S:45])[NH:32][C:31]4=[O:30])=[CH:44][CH:43]=3)[CH:7]=[CH:6][CH:5]=1)=[CH:16][CH:15]=[CH:14][C:13]=2[C:18]([F:21])([F:19])[F:20])(=[O:23])[C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1Participants
3
Procedure
The title compound was prepared from [4-(3-amino-phenyl)-8-trifluoromethyl-quinolin-3-yl]-phenyl-methanone and 4-(4-oxo-2-thioxo-thiazolidin-5-ylidenemethyl)-benzaldehyde according to the procedure of Example 66. MS (ES) m/z 623.8.
Sources & evidence
- ORD record
- ord-a5196cb4a9be496fbb9afb007c37fbc9
- Source dataset
- uspto-grants-2009_08
- Patent number
- US07576215B2
Reaction notes
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