HCID 66913849, compound → HCID 66914272, compound

HRID 2104588Notes

Reaction equation

HRID 2104588 reaction equation
[C:1]([C:9]1[CH:10]=[N:11][C:12]2[C:17]([C:18]=1[C:19]1[CH:20]=[C:21]([NH:25][C:26]([NH:28][C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=3[N+:35]([O-])=O)=[O:27])[CH:22]=[CH:23][CH:24]=1)=[CH:16][CH:15]=[CH:14][C:13]=2[C:38]([F:41])([F:40])[F:39])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>[Pd]>[NH2:35][C:30]1[CH:31]=[CH:32][CH:33]=[CH:34][C:29]=1[NH:28][C:26]([NH:25][C:21]1[CH:22]=[CH:23][CH:24]=[C:19]([C:18]2[C:17]3[C:12](=[C:13]([C:38]([F:41])([F:39])[F:40])[CH:14]=[CH:15][CH:16]=3)[N:11]=[CH:10][C:9]=2[CH:1]([OH:8])[C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH:20]=1)=[O:27]

Participants

3

Reactant 1

HCID 66913849HCID 66913849, compound

Product 1

HCID 66914272HCID 66914272, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The title compound was prepared from N-{3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}-N′-(2-nitrophenyl)urea by hydrogenation (Pd/C, 5 psi of H2). MS (ES) m/z 526.9.

Sources & evidence

ORD record
ord-35870597b8ab4c979c0ab84e6856083b
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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