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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104589Generated: October 30, 2026

1-Chloro-2-isothiocyanatobenzene → N-{3-[3-Benzoyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}-N'-(2-Chlorophenyl) Thiourea

https://huagongshe.com/reaction/2104589

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Chloro-2-isothiocyanatobenzeneHCID 123171—
Reactant[4-(3-Aminophenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)MethanoneHCID 11326798—
ProductN-{3-[3-Benzoyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}-N'-(2-Chlorophenyl) ThioureaHCID 86598754—

Reaction Steps

The title compound was prepared from [4-(3-amino-phenyl)-8-trifluoromethyl-quinolin-3-yl]-phenyl-methanone and 2-chlorophenyl isothiocyanate according to the procedure of Example 65. MS (ES) m/z 559.8.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-bb6eaf6641864f19b91072337bfac8c3
Source noteuspto-grants-2009_08