HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Fluorophenyl)acetaldehyde → 3-[3-(4-Fluorophenyl)-8-(trifluoromethyl)quinolin-4-yl]phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Fluorophenyl)acetaldehyde | HCID 11126322 | — |
| Reactant | [2-Amino-3-(trifluoromethyl)phenyl](3-hydroxyphenyl)methanone | HCID 66586253 | — |
| Product | 3-[3-(4-Fluorophenyl)-8-(trifluoromethyl)quinolin-4-yl]phenol | HCID 66913752 | — |
Reaction Steps
The title compound was prepared from [2-amino-3-(trifluoromethyl)phenyl]-(3-hydroxy-phenyl)methanone and (4-Fluoro-phenyl)-acetaldehyde following the procedure of Example 457: MS m/z 384; HRMS: calcd for C22H13F4NO+H+, 384.10060; found (ESI, [M+H]+), 384.0997.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576215B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-e157d2fb36754abeaf7c606f4df02c97 |
| Source note | uspto-grants-2009_08 |