2-(2,6-Dichlorophenyl)acetaldehyde → HCID 66913775, compound

HRID 2104632Notes

Reaction equation

HRID 2104632 reaction equation
[NH2:1][C:2]1[C:7]([C:8]([F:11])([F:10])[F:9])=[CH:6][CH:5]=[CH:4][C:3]=1[C:12]([C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([OH:20])[CH:15]=1)=O.[Cl:21][C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([Cl:28])[C:23]=1[CH2:29][CH:30]=O>>[Cl:21][C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([Cl:28])[C:23]=1[C:29]1[CH:30]=[N:1][C:2]2[C:3]([C:12]=1[C:14]1[CH:15]=[C:16]([OH:20])[CH:17]=[CH:18][CH:19]=1)=[CH:4][CH:5]=[CH:6][C:7]=2[C:8]([F:11])([F:10])[F:9]

Participants

3

Reactant 2

HCID 122635642-(2,6-Dichlorophenyl)acetaldehydeHCID 66586253[2-Amino-3-(trifluoromethyl)phenyl](3-hydroxyphenyl)methanone

Product 1

HCID 66913775HCID 66913775, compound

Procedure

The title compound was prepared from [2-amino-3-(trifluoromethyl)phenyl]-(3-hydroxy-phenyl)methanone and (2,6-dichloro-phenyl)-acetaldehyde following the procedure of Example 457: MS (ES) m/z 431.8; HRMS: calcd for C22H12Cl2F3NO+H+, 434.03208; found (ESI, [M+H]+), 434.033.

Sources & evidence

ORD record
ord-6a871c35c6e844a1aa02ad2adb81976f
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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