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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104645Generated: October 26, 2026

1-(Bromomethyl)-4-(1,1-dimethylethyl)benzene → [4-{3-[(4-Tert-Butylbenzyl)Oxy]Phenyl}-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)-Methanone

https://huagongshe.com/reaction/2104645

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Bromomethyl)-4-(1,1-dimethylethyl)benzeneHCID 87836—
Reactant[4-(3-Hydroxyphenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)MethanoneHCID 11773771—
Product[4-{3-[(4-Tert-Butylbenzyl)Oxy]Phenyl}-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)-MethanoneHCID 66914447—

Reaction Steps

The title compound was prepared from [4-(3-hydroxyphenyl)-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone and 1-Bromomethyl-4-tert-butyl-benzene following the procedure of Example 478: MS (ESI) m/z 540.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-67d42377bf3d4d8ab549f3aa81c196e8
Source noteuspto-grants-2009_08