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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104646Generated: October 25, 2026

1-(Bromomethyl)-4-(propan-2-yl)benzene → [4-{3-[(4-Isopropylbenzyl)Oxy]Phenyl}-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)-Methanone

https://huagongshe.com/reaction/2104646

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Bromomethyl)-4-(propan-2-yl)benzeneHCID 47719—
Reactant[4-(3-Hydroxyphenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)MethanoneHCID 11773771—
Product[4-{3-[(4-Isopropylbenzyl)Oxy]Phenyl}-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)-MethanoneHCID 66913754—

Reaction Steps

The title compound was prepared from [4-(3-hydroxyphenyl)-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone and 1-Bromomethyl-4-isopropylbenzene following the procedure of Example 478: MS (ESI) m/z 526;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-e0bc38bb47124b848c9fc8641b1a71b8
Source noteuspto-grants-2009_08