HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-fluorobenzyl bromide → [4-{3-[(4-Chloro-2-Fluorobenzyl)Oxy]Phenyl}-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)-Methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-fluorobenzyl bromide | HCID 2736551 | — |
| Reactant | [4-(3-Hydroxyphenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)Methanone | HCID 11773771 | — |
| Product | [4-{3-[(4-Chloro-2-Fluorobenzyl)Oxy]Phenyl}-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)-Methanone | HCID 66914138 | — |
Reaction Steps
The title compound was prepared from [4-(3-hydroxyphenyl)-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone and 1-Bromomethyl-4-chloro-2-fluoro-benzene following the procedure of Example 478: MS (ESI) m/z 536.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576215B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-77a81da21e914333bec67fe0b1d1ad79 |
| Source note | uspto-grants-2009_08 |