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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104648Generated: October 30, 2026

2-Bromomethylnaphthalene → [4-[3-(2-Naphthylmethoxy)Phenyl]-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)-Methanone

https://huagongshe.com/reaction/2104648

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-BromomethylnaphthaleneHCID 70320—
Reactant[4-(3-Hydroxyphenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)MethanoneHCID 11773771—
Product[4-[3-(2-Naphthylmethoxy)Phenyl]-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)-MethanoneHCID 66913805—

Reaction Steps

The title compound was prepared from [4-(3-hydroxyphenyl)-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone and 2-Bromomethyl-naphthalene following the procedure of Example 478: MS (ESI) m/z 534.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-bdb0c23224984fe9baf68f5599f2d4b0
Source noteuspto-grants-2009_08