5-Bromo-2-methyl-2-pentene → [4-{3-[(4-Methylpent-3-enyl)Oxy]Phenyl}-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)Methanone

HRID 2104652Notes

Reaction equation

HRID 2104652 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[C:13]([C:18]([F:21])([F:20])[F:19])[CH:14]=[CH:15][CH:16]=3)[N:11]=[CH:10][C:9]=2[C:22]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[O:23])[CH:5]=[CH:6][CH:7]=1.Br[CH2:31][CH2:32][CH:33]=[C:34]([CH3:36])[CH3:35]>>[CH3:35][C:34]([CH3:36])=[CH:33][CH2:32][CH2:31][O:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[C:13]([C:18]([F:21])([F:19])[F:20])[CH:14]=[CH:15][CH:16]=3)[N:11]=[CH:10][C:9]=2[C:22]([C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=2)=[O:23])[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 1375215-Bromo-2-methyl-2-penteneHCID 11773771[4-(3-Hydroxyphenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)Methanone

Product 1

HCID 66913883[4-{3-[(4-Methylpent-3-enyl)Oxy]Phenyl}-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)Methanone

Procedure

The title compound was prepared from [4-(3-hydroxyphenyl)-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone and 5-Bromo-2-methyl-pent-2-ene following the procedure of Example 478: MS (ESI) m/z 476.

Sources & evidence

ORD record
ord-127ae0e1265d4b429d1b4b24e1a9b1e4
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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