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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104659Generated: October 30, 2026

2-(Bromomethyl)-5-nitrofuran → [4-{3-[(5-Nitro-2-Furyl)Methoxy]Phenyl}-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)Methanone

https://huagongshe.com/reaction/2104659

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Bromomethyl)-5-nitrofuranHCID 719824—
Reactant[4-(3-Hydroxyphenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)MethanoneHCID 11773771—
Product[4-{3-[(5-Nitro-2-Furyl)Methoxy]Phenyl}-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)MethanoneHCID 66913929—

Reaction Steps

The title compound was prepared from [4-(3-hydroxyphenyl)-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone and 2-Bromomethyl-5-nitro-furan following the procedure of Example 478: MS (ES) m/z 517.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-21f97cc963724fdbb2992e9d26d88d4a
Source noteuspto-grants-2009_08