[4-(3-Hydroxyphenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)Methanone → HCID 66913648, compound

HRID 2104661Notes

Reaction equation

HRID 2104661 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[C:13]([C:18]([F:21])([F:20])[F:19])[CH:14]=[CH:15][CH:16]=3)[N:11]=[CH:10][C:9]=2[C:22]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[O:23])[CH:5]=[CH:6][CH:7]=1.[Br:30][C:31]1[CH:36]=[CH:35][C:34]([CH2:37]Br)=[C:33]([O:39][CH3:40])[CH:32]=1>>[Br:30][C:31]1[CH:36]=[CH:35][C:34]([CH2:37][O:1][C:2]2[CH:3]=[C:4]([C:8]3[C:17]4[C:12](=[C:13]([C:18]([F:21])([F:19])[F:20])[CH:14]=[CH:15][CH:16]=4)[N:11]=[CH:10][C:9]=3[C:22]([C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=3)=[O:23])[CH:5]=[CH:6][CH:7]=2)=[C:33]([O:39][CH3:40])[CH:32]=1

Participants

3

Reactant 2

HCID 11773771[4-(3-Hydroxyphenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)MethanoneHCID 534180324-Bromo-1-(bromomethyl)-2-methoxybenzene

Product 1

HCID 66913648HCID 66913648, compound

Procedure

The title compound was prepared from [4-(3-hydroxyphenyl)-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone and 4-Bromo-1-bromomethyl-2-methoxy-benzene following the procedure of Example 478: MS (ES) m/z 592.1.

Sources & evidence

ORD record
ord-a3c1f5c85c9f443fb1875ef2c67a9df9
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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