1,3-Benzodioxole, 5-(bromomethyl)- → HCID 66914087, compound

HRID 2104664Notes

Reaction equation

HRID 2104664 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[C:13]([C:18]([F:21])([F:20])[F:19])[CH:14]=[CH:15][CH:16]=3)[N:11]=[CH:10][C:9]=2[C:22]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[O:23])[CH:5]=[CH:6][CH:7]=1.Br[CH2:31][C:32]1[CH:40]=[CH:39][C:35]2[O:36][CH2:37][O:38][C:34]=2[CH:33]=1>>[O:36]1[C:35]2[CH:39]=[CH:40][C:32]([CH2:31][O:1][C:2]3[CH:3]=[C:4]([C:8]4[C:17]5[C:12](=[C:13]([C:18]([F:21])([F:19])[F:20])[CH:14]=[CH:15][CH:16]=5)[N:11]=[CH:10][C:9]=4[C:22]([C:24]4[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=4)=[O:23])[CH:5]=[CH:6][CH:7]=3)=[CH:33][C:34]=2[O:38][CH2:37]1

Participants

3

Reactant 2

HCID 64514231,3-Benzodioxole, 5-(bromomethyl)-HCID 11773771[4-(3-Hydroxyphenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)Methanone

Product 1

HCID 66914087HCID 66914087, compound

Procedure

The title compound was prepared from [4-(3-hydroxyphenyl)-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone and 5-Bromomethyl-benzo[1,3]dioxole following the procedure of Example 478: MS (ESI) m/z 528; HRMS: calcd for C31H20F3NO4+H+, 528.14172; found (ESI, [M+H]+), 528.1435.

Sources & evidence

ORD record
ord-2d05e4be4d794ce1b97a813bbb64169f
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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