5-(Bromomethyl)-2,1,3-benzoxadiazole → HCID 66913761, compound

HRID 2104665Notes

Reaction equation

HRID 2104665 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[C:13]([C:18]([F:21])([F:20])[F:19])[CH:14]=[CH:15][CH:16]=3)[N:11]=[CH:10][C:9]=2[C:22]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[O:23])[CH:5]=[CH:6][CH:7]=1.Br[CH2:31][C:32]1[CH:33]=[CH:34][C:35]2[C:36]([CH:40]=1)=[N:37][O:38][N:39]=2>>[N:39]1[O:38][N:37]=[C:36]2[CH:40]=[C:32]([CH2:31][O:1][C:2]3[CH:3]=[C:4]([C:8]4[C:17]5[C:12](=[C:13]([C:18]([F:21])([F:19])[F:20])[CH:14]=[CH:15][CH:16]=5)[N:11]=[CH:10][C:9]=4[C:22]([C:24]4[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=4)=[O:23])[CH:5]=[CH:6][CH:7]=3)[CH:33]=[CH:34][C:35]=12

Participants

3

Reactant 2

HCID 27355875-(Bromomethyl)-2,1,3-benzoxadiazoleHCID 11773771[4-(3-Hydroxyphenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)Methanone

Product 1

HCID 66913761HCID 66913761, compound

Procedure

The title compound was prepared from [4-(3-hydroxyphenyl)-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone and 5-Bromomethyl-benzo[1,2,5]oxadiazole following the procedure of Example 478: MS (ESI) m/z 526; MS (ESI) m/z 524; HRMS: calcd for C30H18F3N3O3+H+, 526.13730; found (ESI, [M+H]+), 526.1356.

Sources & evidence

ORD record
ord-4a34432abf934e1cbff9ca8989ba6ac6
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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