HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Bromomethyl)-1,3-dimethylbenzene → 3-Benzyl-4-{3-[(2,6-Dimethylbenzyl)Oxy]Phenyl}-8-(Trifluoromethyl)Quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Bromomethyl)-1,3-dimethylbenzene | HCID 13929124 | — |
| Reactant | 3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenol | HCID 53630755 | — |
| Product | 3-Benzyl-4-{3-[(2,6-Dimethylbenzyl)Oxy]Phenyl}-8-(Trifluoromethyl)Quinoline | HCID 66913629 | — |
Reaction Steps
The title compound was prepared from 3-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenol and 2-Bromomethyl-1,3-dimethyl-benzene following the procedure of Example 478: MS m/z 498; HRMS: calcd for C32H26F3NO+H+, 498.20392; found (ESI, [M+H]+), 498.2038.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576215B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-18a78afc8e4e4821852b05473af5614c |
| Source note | uspto-grants-2009_08 |