HCID 66913812, compound → HCID 44472991, compound
Reaction equation
[NH2:1][C:2]1[C:7]([C:8]([F:11])([F:10])[F:9])=[CH:6][CH:5]=[CH:4][C:3]=1[C:12]([C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([O:20][C:21]2[CH:26]=[CH:25][C:24]([O:27][CH3:28])=[CH:23][CH:22]=2)[CH:15]=1)=O.F[C:30]1[C:35](C(F)(F)F)=[CH:34][CH:33]=[CH:32][C:31]=1[C:40]([C:42]1C=CC=C(OC2C=CC(OC)=CC=2)[CH:43]=1)=O>>[CH2:40]([C:42]1[CH:43]=[N:1][C:2]2[C:3]([C:12]=1[C:14]1[CH:19]=[CH:18][CH:17]=[C:16]([O:20][C:21]3[CH:26]=[CH:25][C:24]([O:27][CH3:28])=[CH:23][CH:22]=3)[CH:15]=1)=[CH:4][CH:5]=[CH:6][C:7]=2[C:8]([F:11])([F:10])[F:9])[C:31]1[CH:32]=[CH:33][CH:34]=[CH:35][CH:30]=1Participants
3
Procedure
[2-amino-3-(trifluoromethyl)phenyl][3-(4-methoxyphenoxy)phenyl]methanone: The title compound was prepared from (2-fluoro-3-trifluoromethylphenyl)-[3-(4-methoxy-phenoxy)-phenyl]methanone (0.64 g, 0.0015 mole) following the procedure of Example 457, Step 3: MS (ESI) m/z 388;
Sources & evidence
- ORD record
- ord-bb49c53cc8de4372a7622bec8f09cdc3
- Source dataset
- uspto-grants-2009_08
- Patent number
- US07576215B2
Reaction notes
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