5-Indolylboronic acid → HCID 66913727, compound

HRID 2104677Notes

Reaction equation

HRID 2104677 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[C:13]([C:18]([F:21])([F:20])[F:19])[CH:14]=[CH:15][CH:16]=3)[N:11]=[CH:10][C:9]=2[C:22]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[O:23])[CH:5]=[CH:6][CH:7]=1.[NH:30]1[C:38]2[C:33](=[CH:34][C:35](B(O)O)=[CH:36][CH:37]=2)[CH:32]=[CH:31]1>>[NH:30]1[C:38]2[C:33](=[CH:34][C:35]([O:1][C:2]3[CH:3]=[C:4]([C:8]4[C:17]5[C:12](=[C:13]([C:18]([F:21])([F:19])[F:20])[CH:14]=[CH:15][CH:16]=5)[N:11]=[CH:10][C:9]=4[C:22]([C:24]4[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=4)=[O:23])[CH:5]=[CH:6][CH:7]=3)=[CH:36][CH:37]=2)[CH:32]=[CH:31]1

Participants

3

Reactant 2

HCID 27343615-Indolylboronic acidHCID 11773771[4-(3-Hydroxyphenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)Methanone

Product 1

HCID 66913727HCID 66913727, compound

Procedure

The title compound was prepared from [4-(3-hydroxy-phenyl)-8-trifluoromethylquinolin-3-yl]-phenyl methanone and 5-Indolylboronic acid, following the procedure of Example 519: MS m/z 509; MS m/z 507.

Sources & evidence

ORD record
ord-c9721323e7494b39bbb5c915d0da2906
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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