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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104692Generated: October 29, 2026

5-Fluorosalicylaldehyde → 2-[({3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}Amino)Methyl]-4-Fluorophenol

https://huagongshe.com/reaction/2104692

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-FluorosalicylaldehydeHCID 2737328—
Reactant3-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamineHCID 11234297—
Product2-[({3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}Amino)Methyl]-4-FluorophenolHCID 66913654—

Reaction Steps

The title compound was prepared from {3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amine and 5-fluoro-2-hydroxybenzaldehyde according to the procedure of step 1, Example 66. MS (ESI) m/z 503; MS (ESI) m/z 501.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-f290892a54a248aea461c434725df49a
Source noteuspto-grants-2009_08