2-Chloro-3-quinolinecarboxaldehyde → HCID 86598763, compound

HRID 2104702Notes

Reaction equation

HRID 2104702 reaction equation
[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:27])[F:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:29][C:30]1[C:39]([CH:40]=O)=[CH:38][C:37]2[C:32](=[CH:33][CH:34]=[CH:35][CH:36]=2)[N:31]=1>>[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH:24][CH2:40][C:39]3[C:30]([Cl:29])=[N:31][C:32]4[C:37]([CH:38]=3)=[CH:36][CH:35]=[CH:34][CH:33]=4)[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:26])[F:27])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 6909582-Chloro-3-quinolinecarboxaldehydeHCID 112342973-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamine

Product 1

HCID 86598763HCID 86598763, compound

Procedure

The title compound was prepared from {3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amine and 2-chloroquinoline-3-carboxaldehyde to the procedure of step 1, Example 66. MS (ESI) m/z 554.

Sources & evidence

ORD record
ord-f4c4da41c95f4f19abb8b2223e953ff4
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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