Chlorophenyl isocyanate → HCID 86598768, compound

HRID 2104721Notes

Reaction equation

[F:1][C:2]([F:31])([F:30])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[CH:10]=[N:11][C:12]2[C:17]([C:18]=1[C:19]1[CH:20]=[C:21]([NH2:25])[CH:22]=[CH:23][CH:24]=1)=[CH:16][CH:15]=[CH:14][C:13]=2[C:26]([F:29])([F:28])[F:27].[Cl:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][C:34]=1[N:39]=[C:40]=[O:41]>>[Cl:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][C:34]=1[NH:39][C:40]([NH:25][C:21]1[CH:22]=[CH:23][CH:24]=[C:19]([C:18]2[C:17]3[C:12](=[C:13]([C:26]([F:27])([F:28])[F:29])[CH:14]=[CH:15][CH:16]=3)[N:11]=[CH:10][C:9]=2[C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=2[C:2]([F:30])([F:1])[F:31])[CH:20]=1)=[O:41]

Participants

Reactant 2

HCID 76833Chlorophenyl isocyanate

HCID 86598769HCID 86598769, compound

Product 1

HCID 86598768HCID 86598768, compound

Procedure

The title compound was prepared from {3-[3-(2-trifluoromethylphenyl)-8-(trifluoromethyl)quinolin-4-yl]phenyl}amine and 2-chlorophenyl isocyanate in substantially the same manner as described in Example 65; off-white solid: mp 230-232° C.; MS (EI) m/z 587(M+H)+.

Sources & evidence

ORD record: ord-b960fa8a619f47f3a2f122235659ad53
Source dataset: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07576215B2

Reaction notes

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