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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104723Generated: October 27, 2026

2-Fluorophenyl isothiocyanate → N-{3-[3-Benzoyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}-N'-(2-Fluorophenyl)Thiourea

https://huagongshe.com/reaction/2104723

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluorophenyl isothiocyanateHCID 97520—
Reactant[4-(3-Aminophenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)MethanoneHCID 11326798—
ProductN-{3-[3-Benzoyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}-N'-(2-Fluorophenyl)ThioureaHCID 86598770—

Reaction Steps

The title compound was prepared from [4-(3-amino-phenyl)-8-trifluoromethyl-quinolin-3-yl]-phenyl-methanone and 2-fluorophenyl isothiocyanate according to the procedure of Example 65. MS (ESI) m/z 546.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-afc837c020a94e86920eed459d4c368c
Source noteuspto-grants-2009_08