Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104727Generated: October 31, 2026

[4-Chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone → N-{3-[3-Benzoyl-8-(Trifluoromethyl)Quinolin-4-yl]Benzyl}-N'-(2-Fluorophenyl)Urea

https://huagongshe.com/reaction/2104727

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[4-Chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanoneHCID 16090325—
Reactant4-[3-(2-Fluoro-phenyl)-ureidomethyl]phenylboronic acidHCID 66913771—
ProductN-{3-[3-Benzoyl-8-(Trifluoromethyl)Quinolin-4-yl]Benzyl}-N'-(2-Fluorophenyl)UreaHCID 66914239—

Reaction Steps

The title compound was prepared from 4-[3-(2-Fluoro-phenyl)-ureidomethyl]phenylboronic acid and [4-chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone according to the procedure of Example 1. MS (ES) m/z 541.9.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-41deac266ed44398895079f093e04e0e
Source noteuspto-grants-2009_08