(3-hydroxyphenyl)boronic Acid → HCID 66586289, compound

HRID 2104731Notes

Reaction equation

HRID 2104731 reaction equation
Cl[C:2]1[C:11]2[C:6](=[C:7]([C:12]([F:15])([F:14])[F:13])[CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][C:3]=1[C:16]#[N:17].[OH:18][C:19]1[CH:20]=[C:21](B(O)O)[CH:22]=[CH:23][CH:24]=1>>[OH:18][C:19]1[CH:24]=[C:23]([C:2]2[C:11]3[C:6](=[C:7]([C:12]([F:15])([F:14])[F:13])[CH:8]=[CH:9][CH:10]=3)[N:5]=[CH:4][C:3]=2[C:16]#[N:17])[CH:22]=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 2734359(3-hydroxyphenyl)boronic AcidHCID 669136344-Chloro-8-(trifluoromethyl)-3-quinolinecarbonitrile

Product 1

HCID 66586289HCID 66586289, compound

Procedure

The title compound was prepared from 4-chloro-8-(trifluoromethyl)quinoline-3-carbonitrile and 3-hydroxyphenylboronic acid according to the procedure of Example 1. HRMS: calcd for C17H9F3N2O+H+, 315.07397; found (ESI, [M+H]+), 315.0752.

Sources & evidence

ORD record
ord-13cc8a5b686741918a7055656cd30458
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

Loading…