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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104741Generated: October 26, 2026

Chlorophenyl isocyanate → 4-[3-({[(2-Chlorophenyl)Amino]Carbonyl}Amino)Phenyl]-8-(Trifluoromethyl) Quinoline-3-Carboxylic Acid

https://huagongshe.com/reaction/2104741

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorophenyl isocyanateHCID 76833—
ReactantEthyl 4-(3-aminophenyl)-8-(trifluoromethyl)quinoline-3-carboxylateHCID 66913532—
Product4-[3-({[(2-Chlorophenyl)Amino]Carbonyl}Amino)Phenyl]-8-(Trifluoromethyl) Quinoline-3-Carboxylic AcidHCID 66913960—

Reaction Steps

The title compound was prepared from ethyl 4-(3-aminophenyl)-8-(trifluoromethyl)quinoline-3-carboxylate and 2-chlorophenyl isocyanate according to the procedure of Example 65. MS (ES) m/z 483.9.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-a657163ba78740f996191aca407e8451
Source noteuspto-grants-2009_08