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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104745Generated: October 30, 2026

[4-Chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone → {4-[({3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}Thio)Methyl]Phenyl}Acetic Acid

https://huagongshe.com/reaction/2104745

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[4-Chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanoneHCID 16090325—
Reactant3-(4-Carboxymethyl-benzylsulfanyl)phenylboronic acidHCID 66913779—
Product{4-[({3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}Thio)Methyl]Phenyl}Acetic AcidHCID 66913527—

Reaction Steps

The title compound was prepared from 3-(4-carboxymethyl-benzylsulfanyl)phenylboronic acid and [4-chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone according to the procedure of Example 1. MS (ES) m/z 541.9.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-c9336be9bd2c41ca96c23df49104e1c8
Source noteuspto-grants-2009_08