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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104759Generated: October 30, 2026

5-Fluoro-2-methoxybenzaldehyde → {3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-YL]phenyl}(5-fluoro-2-methoxybenzyl)amine

https://huagongshe.com/reaction/2104759

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Fluoro-2-methoxybenzaldehydeHCID 2734943—
Reactant3-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamineHCID 11234297—
Product{3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-YL]phenyl}(5-fluoro-2-methoxybenzyl)amineHCID 66914438—

Reaction Steps

The title compound was prepared from {3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amine and 5-fluoro-2-methoxy-benzaldehyde according to the procedure of Example 66. MS (ESI) m/z 517.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-6eb9cc370e3a4153b1bc7827b2c23348
Source noteuspto-grants-2009_08