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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104773Generated: October 25, 2026

5-Fluoro-2-(trifluoromethyl)benzaldehyde → {3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}[5-Fluoro-2-(Trifluoromethyl)Benzyl]Amine

https://huagongshe.com/reaction/2104773

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Fluoro-2-(trifluoromethyl)benzaldehydeHCID 2737538—
Reactant3-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamineHCID 11234297—
Product{3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}[5-Fluoro-2-(Trifluoromethyl)Benzyl]AmineHCID 86598776—

Reaction Steps

The title compound was prepared from {3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amine and 5-fluoro-2-trifluoromethyl-benzaldehyde according to the procedure of Example 66. MS (ESI) m/z 555.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-9ad863807951489a8564970c831f5d5d
Source noteuspto-grants-2009_08