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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104774Generated: October 25, 2026

2,5-Dimethylphenol → 3-Benzyl-4-{3-[(2,5-Dimethylphenoxy)Methyl]Phenyl}-8-(Trifluoromethyl)Quinoline

https://huagongshe.com/reaction/2104774

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-DimethylphenolHCID 7267—
Reactant{3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}MethanolHCID 11223110—
Product3-Benzyl-4-{3-[(2,5-Dimethylphenoxy)Methyl]Phenyl}-8-(Trifluoromethyl)QuinolineHCID 66913624—

Reaction Steps

The title compound was prepared from {3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}methanol and 2,5-dimethylphenol according to the procedure of Example 69. MS (ESI) m/z 498.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-30c85f88c0ff4ed6a516f75da3a0a398
Source noteuspto-grants-2009_08