3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenol → HCID 86598779, compound

HRID 2104779Notes

Reaction equation

HRID 2104779 reaction equation
[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20](O)[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:27])[F:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:29][O:30][C:31](=[O:41])[CH2:32][C:33]1[N:34]([CH3:40])[C:35]([CH2:38][OH:39])=[CH:36][CH:37]=1>>[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:23]=[CH:22][C:21]([O:39][CH2:38][C:35]3[N:34]([CH3:40])[C:33]([CH2:32][C:31]([O:30][CH3:29])=[O:41])=[CH:37][CH:36]=3)=[CH:20][CH:19]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:26])([F:27])[F:28])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 536307553-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenolHCID 66914478HCID 66914478, compound

Product 1

HCID 86598779HCID 86598779, compound

Procedure

The title compound was prepared from 3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenol and (5-hydroxymethyl-1-methyl-1H-pyrrol-2-yl)-acetic acid methyl ester according to the procedure of Example 69. MS (ESI) m/z 545.

Sources & evidence

ORD record
ord-24a9c7277fa54cdd94a0e009242346af
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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